Dr Fragkou Martha
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Alcohol and Cannabis Use Disorders

This issue of the Journal is focused on providing a deeper understanding of the factors underlying alcohol and cannabis use and misuse in relation to the development of substance use disorders and interactions with other psychiatric illnesses. The prevalence of alcohol use disorder in the United States is high. Data from 2019 suggest that 14.5 million individuals...
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The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia

At its December 2015 meeting, The APA Board of Trustees approved the APA Practice Guideline Writing Group’s “Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia.” [The full guideline is available at http://psychiatryonline.org/doi/book/10.1176/appi.books.9780890426807] Introduction The goal of this guideline is to improve the care of patients with dementia who...
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Trauma and Psychosis: An Analysis of the National Comorbidity Survey

Abstract Objective: The authors hypothesized that the likelihood of psychosis classification would increase with traumatic experiences. Method: Data from the National Comorbidity Survey were used to estimate the relationship between interpersonal trauma and the likelihood of a classification of psychosis. Results: Childhood physical abuse predicted psychosis, and there was a significant cumulative relationship between trauma and psychosis, with number of...
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Increased Stress-Induced Inflammatory Responses in Male Patients With Major Depression and Increased Early Life Stress

Abstract Objective: The authors sought to determine innate immune system activation following psychosocial stress in patients with major depression and increased early life stress. Method: Plasma interleukin (IL)-6, lymphocyte subsets, and DNA binding of nuclear factor (NF)-kB in peripheral blood mononuclear cells were compared in medically healthy male subjects with current major depression and increased early life stress...
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Internet Gaming Disorder: Investigating the Clinical Relevance of a New Phenomenon

Abstract Objective: The American Psychiatric Association (APA) identified Internet gaming disorder as a new potential psychiatric disorder and has recognized that little is known about the prevalence, validity, or cross-cultural robustness of proposed Internet gaming disorder criteria. In response to this gap in our understanding, the present study, a first for this research topic, estimated...
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